Which enzyme's inhibitors are commonly used to treat glaucoma?

Carbonic anhydrase inhibitors are commonly used to treat glaucoma because they work by reducing the production of aqueous humor, the fluid within the eye. This decrease in aqueous humor production leads to a reduction in intraocular pressure, which is crucial in managing glaucoma and preventing damage to the optic nerve. By inhibiting the carbonic anhydrase enzyme, these medications effectively lower the pressure in the eye, making them a primary choice in glaucoma treatment.

Other classes of medications, such as prostaglandin analogs, are also used to lower intraocular pressure, but they function primarily by enhancing the outflow of aqueous humor rather than inhibiting its production. Acetylcholinesterase inhibitors are not commonly used for glaucoma; instead, they influence the nervous system and muscle activity. Lactate dehydrogenase does not have a role in the treatment of glaucoma, as it is involved in metabolic processes rather than in ocular pressure regulation.