When should topical corticosteroids not be used in uveitis treatment?

Topical corticosteroids are contraindicated in the presence of a corneal ulcer due to the risk of exacerbating the situation. Corticosteroids suppress the local immune response and can delay healing, making the cornea more susceptible to infection and further damage. In the case of a corneal ulcer, using corticosteroids could lead to complications such as perforation or worsening of the ulcer, ultimately deteriorating the overall ocular health of the patient.

In contrast, systemic antimicrobials may be administered concurrently with corticosteroids in other scenarios, as they address potential underlying infectious causes without conflict. The presence of uveal cysts typically does not preclude the use of corticosteroids, as they are not usually associated with significant inflammation that could arise from uveitis. Furthermore, patient comfort considerations are important in therapeutic decisions but do not specifically relate to the safety and effectiveness of corticosteroid use in treating uveitis. Thus, understanding the implications of corticosteroid use in the context of a corneal ulcer is critical for appropriate management in ocular conditions.