What condition may present with miosis as a clinical sign?

Miosis, or constriction of the pupil, is often associated with uveitis, which is inflammation of the uveal tract of the eye. When uveitis occurs, various inflammatory mediators can affect the iris and ciliary body, leading to pupillary constriction. This is a protective reflex response as part of the body’s attempt to minimize light exposure in an inflamed environment and reduce pain.

In uveitis, the inflammation can also lead to additional clinical signs such as redness, photosensitivity, and aqueous flare due to proteins leaking into the anterior chamber. The presence of miosis can be particularly notable, as it distinguishes uveitis from other conditions that may result in pupil dilation or a mid-position pupil.

In contrast, other conditions listed, such as acute glaucoma, retinal detachment, and conjunctivitis, generally do not present with miosis. Acute glaucoma typically results in a dilated pupil due to increased intraocular pressure. Retinal detachment may affect vision but does not typically cause miosis. Conjunctivitis primarily affects the conjunctiva, leading to signs like redness and discharge rather than direct changes in pupil size.